Biopharmaceutical Technician

Full Job Description

NIST works with industry and science to advance innovation and improve quality of life. We're looking for a Biopharmaceutical Technician to join our team!

The Bioanalytical Science Group at NIST develops and validates reference methods, reference materials and reference data to enable accurate characterization of complex biological systems.

Our work underpins analytical measurements across diverse applications including mass spectrometry-based analysis of proteins, glycans and oligonucleotides.

One year (52 weeks) of specialized experience equivalent to the GS-8 (ZT-II at NIST) level.

Specialized experience is defined as: Performing analytical characterization of proteins, peptides, and/or nucleic acid-based materials.

Developing sample preparation techniques to assess identity, concentration, and/or sequence of these materials.

Performing liquid chromatography-mass spectrometry analysis of hydrolyzed or enzymatically digested proteins and/or mRNA Maintaining accurate experimental records and summarizing data -OR- Master's degree in a field of study that is directly related to the work of the position -OR- Two full years of graduate education (36 semester hours) in a field of study that is directly related to the work of the position -OR- An equivalent combination of specialized experience and graduate education beyond the first 1 1/2 years (27 semester hours) of progressive graduate study.

Graduate education must be in a field of study that is directly related to the work of the position.

Experience refers to paid and unpaid experience, including volunteer work done through National Service programs (e.g., Peace Corps, AmeriCorps) and other organizations (e.g., professional; philanthropic; religious; spiritual; community, student, social).

Volunteer work helps build critical competencies, knowledge, and skills and can provide valuable training and experience that translates directly to paid employment.

You will receive credit for all qualifying experience, including volunteer experience. The qualification requirements in this vacancy announcement are based on the U.S.

Office of Personnel Management (OPM) Qualification Standards Handbook.

If requesting reconsideration of your qualification determination, please refer to the following site: Applicant Reconsideration Major Duties:

In this position, you will: Support the development and maintenance of NIST biomanufacturing reference materials by independently performing analytical characterization of proteins, peptides, and nucleic acid-based materials (including mRNA).

Develop and apply hydrolytic and enzymatic sample preparation techniques to confirm reference material properties, including identity, concentration, and amino acid or nucleic acid sequence.

Independently perform liquid chromatographic-mass spectrometric (LC-MS) analysis of hydrolyzed or enzymatically digested monoclonal antibodies (mAbs) and mRNA to assess quality and quantity and document results.

Troubleshoot experimental issues and optimize sample preparation and instrumental parameters as needed to improve laboratory procedures.

Maintain detailed experimental records, including the electronic location of experimental data, and document any deviations from established protocols.

Summarize research results and contribute to research reports and publications. Adhere to all applicable laboratory safety protocols and maintain a clean working environment.